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Senior Bioinformatics Software Engineer - Production Informatics, Oncology

AstraZeneca Waltham, MA
senior bioinformatics software engineer production informatics oncology data research bioinformatics science oncology data analysis
January 30, 2023
AstraZeneca
Waltham, MA
FULL_TIME

AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. In AstraZeneca Oncology, our goal is to be at the forefront of developing the next generation of cancer therapies.

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals. We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health.

This position can be based in Boston US, Gaithersburg US or Cambridge UK

About AstraZeneca in Waltham, MA

The Waltham R&D site focuses on our small-molecule oncology research in North America, and is situated within a biopharma cluster of research institutions, medical centers, pharmaceutical companies and startups. The Boston region is consistently ranked #1 globally for research, investment, talent recruitment and lab space.

The campus, also known as the Boston BioHub, is one of the largest and most dynamic life-science research hubs in the region. It is home to more than 800 scientists working in nine different pharmaceutical and biotech companies. The site is also home to the AstraZeneca Incubator, a program that helps emerging companies advance novel and innovative healthcare solutions to meet the needs of patients. Plenty of free parking, with charging stations now available for electric vehicles, and shuttle service to local transportation hubs.

About AstraZeneca in Gaithersburg, MD:

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

Main Duties & Responsibilities

There is an exciting opportunity for a talented and motivated bioinformatician to join the group as a Sr. Bioinformatics Software-Engineer. In this role, you will:

  • Build scalable (Cloud and HPC) solutions that work on tens of thousands of CPUs.
  • Develop, test, and support bioinformatics data analysis tools and pipelines for Sequencing data (NGS) at scale.
  • Automate complex data analysis processes.
  • Design and apply innovative computational, machine learning, AI, and statistical algorithms.
  • Validate the quality of the datasets using various tools to assess the correctness of the results.
  • Manage, analyze, and deliver sequencing data (NGS).
Education & Experience Requirements

Degree in Bioinformatics, Computer Science, or Engineering with 5+ years of applied experience in bioinformatics, specifically in sequencing data analysis: DNA-Seq, RNA-Seq, BS-Seq, Single-Cell, ATAC-Seq, etc.

Required Skills
  • Programming skills: Solid Python programming skills, as well as experience in other programming languages.
  • Experience in: Unix, SQL databases, REST APIs, Cloud computing (AWS), and HPC (High Performance Computing)
  • Experience in software development best practices
Desired Skills
  • Awareness of machine learning, and statistical data analysis.
  • An understanding of the contribution of bioinformatics to drug discovery.
  • NGS analyses for Oncology.


Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we're opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what's next?

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it's yours.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

AstraZeneca has taken critical steps to protecting colleagues, loved ones, and patients from COVID-19 and its variants. COVID-19 vaccination is required for all US employees, and weekly PCR COVID-19 testing is required for those who are unvaccinated or have an approved accommodation.

Date Posted
24-Feb-2022

Closing Date

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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